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Matchpoint Therapeutics, Novartis Partner to Develop Covalent Medicines for Inflammatory Diseases

Aim to advance covalent medicines with the potential to address unmet medical needs and historically undruggable targets.

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By: Charlie Sternberg

Associate Editor

Matchpoint Therapeutics, a biotechnology firm specializing in precision covalent medicines, has entered into an exclusive option and license agreement with Novartis to develop and commercialize oral covalent inhibitors targeting a transcription factor associated with multiple inflammatory diseases. The collaboration aims to leverage Matchpoint’s proprietary Advanced Covalent Exploration (ACE) platform to target a novel binding site on a protein previously considered difficult to drug, with th...

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